Within the next year, he landed his first notable acting role, a guest appearance in It's Always Sunny in Philadelphia. In 2007, he had a three-episode stint in the drama Heroes. His other television credits include Bones and Trust Me. He co-starrred as Cameron Parks in the Disney Channel sitcom A.N.T. Farm, which premiered in 2011. He left the show after the second season and Aedin Mincks joined the main cast.
In music, Jeffery is also a rapper, performing under the pseudonym Lil' C-Note. He is currently making a mixtape album.
He has a twin sister, Carla Jeffery, who is an actress.